Immunological Memory and Reinfection by SARS-CoV-2/COVID-19
Main Article Content
Abstract
Introduction: The severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) is a type of coronavirus that causes the coronavirus disease (COVID-19), which has become a significant problem for global public health due to the pandemic and its high transmissibility and mortality. Since the beginning of the SARS-CoV-2 / COVID-19 pandemic, multiple questions have been generated, such as the production of immunological memory and the appearance of cases of reinfection by the same virus.
Objective: Review the microbiological and clinical characteristics, immunological memory, and reinfection by SARS-CoV-2.
Conclusions: The infection by SARS-CoV-2 in patients with mild disease has been associated with protective immunity for a limited time, which could explain the presentation of cases of reinfection after the initial event with a demonstration of the production of Immunoglobulin G antibodies (IgG).
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Creative Commons
License Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
You are free to:
Share - copy and redistribute the material in any medium or format.
Adapt - remix, transform, and build upon the material The licensor cannot revoke these freedoms as long as you follow the license terms.
• Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
• NonCommercial — You may not use the material for commercial purposes.
• ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
• No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
References
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–33. DOI: https://doi.org/10.1056/NEJMoa2001017
Ramiro-mendoza MS. Epidemiología del SARS-CoV-2 Epidemiology SARS-CoV-2. Acta Pediatr Mex. 2020;41(Supl 1):8–14. DOI: https://doi.org/10.18233/APM41No4S1ppS8-S142051
Chen Y, Liu Q, Guo D. Emerging coronaviruses : Genome structure, replication , and pathogenesis. J Med Virol. 2020;92(January):418–23. DOI: https://doi.org/10.1002/jmv.25681
Pastrian-Soto G. Bases Genéticas y Moleculares del COVID-19 (SARS-CoV-2). Mecanismos de Patogénesis y de Respuesta Inmune. Int J Odontostomatol. 2020;14(3):331–7. DOI: https://doi.org/10.4067/S0718-381X2020000300331
Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell. 2020 Apr;181(2):271-280.e8. DOI: https://doi.org/10.1016/j.cell.2020.02.052
Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel C, et al. Functional SARS-CoV-2-specific immune memory persists after mild COVID-19. Cell. 2020;(November):1–56. DOI: https://doi.org/10.1101/2020.08.11.20171843
Morris A, Wells A, Wheeler SE. Assessing Immune Response to SARS-CoV-2 Infection. Inmuno Target Ther. 2020;9:111–4. DOI: https://doi.org/10.2147/ITT.S264138
Biron CA. More things in heaven and earth: Defining innate and adaptive immunity. Nat Immunol. 2010;11(12):1080–2. DOI: https://doi.org/10.1038/ni1210-1080
Slifka MK, Ahmed R. Long-term antibody production is sustained by antibody-secreting cells in the bone marrow following acute viral infection. In: Annals of the New York Academy of Sciences. Blackwell Publishing Inc.; 1996. p. 166–76. DOI: https://doi.org/10.1111/j.1749-6632.1996.tb52958.x
Sette A, Crotty S. Pre-existing immunity to SARS-CoV-2: the knowns and unknowns. Nat Rev Immunol. 2020;20(8):457–8. DOI: https://doi.org/10.1038/s41577-020-0389-z
Ortega E. Is Immunological Memory a Burden in Times of COVID-19? Vol. 41, Trends in Immunology. 2020. DOI: https://doi.org/10.1016/j.it.2020.08.004
López Pérez GT, Ramírez Sandoval M de LP, Torres Altamirano MS. Participantes de la respuesta inmunológica ante la infección por SARS-CoV-2. Alergia, Asma e Inmunol Pediátricas. 2020;29(1):5–15. DOI: https://doi.org/10.35366/93321
Lurie N, Saville M, Hatchett R, Halton J. Developing Covid-19 Vaccines at Pandemic Speed. N Engl J Med. 2020 May;382(21):1969–73. DOI: https://doi.org/10.1056/NEJMp2005630
Patel A, Dong JC, Trost B, Richardson JS, Tohme S, Babiuk S, et al. Pentamers not found in the universal proteome can enhance antigen specific immune responses and adjuvant vaccines. Plos One. 2012;7(8):1–12. DOI: https://doi.org/10.1371/journal.pone.0043802
Wajnberg A, Amanat F, Firpo A, Altman D, Bailey M, Mansour M, et al. Title: SARS-CoV-2 infection induces robust, neutralizing antibody responses that are stable for at least three months. 2020. DOI: https://doi.org/10.1101/2020.07.14.20151126
Rodriguez-morales AJ, Cardona-ospina JA, Villamil-gómez WE. Should we concern about reinfection in COVID-19 ? 2020;25(2):77–8. DOI: https://doi.org/10.22354/in.v25i2.922
Prado B, Becerra M, Guadalupe JJ, Barragan V. A case of SARS-CoV-2 reinfection in Ecuador. Lancet Infect Dis. 2020;2(20):30910.
Yagleiry J, Rodríguez M, Merchán JT, García EO, Elena L, Binaghi C, et al. Tratamiento para COVID 19. Rev Latinoam Infectología Pediátrica. 2020;33:42–51. DOI: https://doi.org/10.35366/96670
KK-W, Hung IF-N, Ip JD, Chu AW-H, Chan W-M, Tam AR et al. Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing. Clin Infect Dis. 2020;1–6.
Iwasaki A. What reinfections mean for COVID-19. Lancet Infect Dis. 2020;2(20):19–20.
Julieta K, Domínguez R, Gabriela E, Rodríguez S, Mejía WM, Jiménez AO, et al. Infectología Pediátrica. Rev Latinoam Infectología Pediátrica. 2020;33:10–32. DOI: https://doi.org/10.35366/96666
Guo CX, He L, Yin JY, Meng XG, Tan W, Yang GP, et al. Epidemiological and clinical features of pediatric COVID-19. BMC Med. 2020;18(1):1–7. DOI: https://doi.org/10.1186/s12916-020-01719-2
Chams N, Chams S, Badran R, Shams A, Araji A, Raad M, et al. COVID-19 : A Multidisciplinary Review. Front Public Heal. 2020;8(July):1–20. DOI: https://doi.org/10.3389/fpubh.2020.00383
Bagheri SH, Asghari A, Farhadi M, Shamshiri AR, Kabir A, Kamrava SK, et al. Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran. Med J Islam Repub Iran. 2020;34(1):1–7. DOI: https://doi.org/10.1101/2020.03.23.20041889
Asociación-Española-de-Pediatría-(AEP). Documento de manejo clinico del paciente pediátrico con infección por SARS-CoV-2. Manejo clínico del Minist Sanid Español. 2020;53(9):1689–99.
Ivveth M, González R, Elena L, Binaghi C, Chávez MS. Infectología Pediátrica Diagnostic methods. Rev Latinoam Infectología Pediátrica. 2020;33:33–41. DOI: https://doi.org/10.35366/96669
Consenso C, Humberto C, Trujillo S, Eduardo R, Quiroga R, Rodríguez AJ, et al. Consenso colombiano de atencion, diagnostico y manejo de la infeccion por SARS CoV 2/COVID 19 en establecimento de atencion de la salud. Infectio. 2020;1–24. DOI: https://doi.org/10.22354/in.v24i3.851