Absence of septum pellucidum in newborn exposed to zika during pregnancy
Main Article Content
Abstract
Zika epidemic and the neurologically effects, mainly microcephaly, have prompted high level alerts in Latin America and Colombia due to the increase in incidence of cases, testifying the need to follow protocols ultimately allowing the correct maternal and neonatal diagnosis. The case of a newborn is presented; she has history of exposure to Zika virus in first trimester, without sonographic abnormalities, neurological deficit or microcephaly who presents an absence of septum pellucidum associated with other malformations in the brain proved y radiology (CT and ecography). Despite this, in several parts of the world there is a significant lack of knowledge of the current literature on this subject which generates a series of barriers that, along with existing prejudices and myths in society, limit the access to PPC.
Downloads
Article Details
Creative Commons
License Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
You are free to:
Share - copy and redistribute the material in any medium or format.
Adapt - remix, transform, and build upon the material The licensor cannot revoke these freedoms as long as you follow the license terms.
• Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
• NonCommercial — You may not use the material for commercial purposes.
• ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
• No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
References
2. Mulkey SB, Vezina G, Bulas DI, Khademian Z, Blask A, Kousa, et al. Neuroimaging Findings in Normocephalic Newborns With Intrauterine Zika Virus Exposure. Pediatr Neurol. 2018;78:75-78.
3. Carod-Artal FJ. Epidemiología y complicaciones neurológicas de la infección por el virus del Zika: un nuevo virus neurotropo emergente en 2016. Rev Neurol. 2016;62(7):317-28.
4. Petribu NCL, Aragao MFV, van der Linden V, Parizel P, Jungmann P, Araújo L, et al. Follow-up brain imaging of 37 children with congenital Zika syndrome: case series study. BMJ. 2017;359:j4188-j.
5. da Silva Pone MV, Moura Pone S, Araujo Zin A, Barros Mendes PH, Senra Aibe M, Barroso de Aguiar E, et al. Zika virus infection in children: epidemiology and clinical manifestations. Childs Nerv Syst. 2018;34(1):63-71.
6. Ribeiro EM, Lopes TF, Kerbage SC, Pessoa ALS, Cavalcanti LPG. From the perception of a cluster of cases of children with microcephaly to congenital Zika syndrome in Brazil: the lessons we have learned and the challenges that lie ahead of us. J Venom Anim Toxins Incl Trop Dis. 2017;23:15.
7. Mlakar J, Korva M, Tul N, Popovic M, Poljsak M, Mraz J, et al. Zika virus associates with microcephaly. N Engl J Med. 2016;374:951-8.
8. Ventura LO, Ventura CV, Lawrence L, van der Linden V, van der Linden A, Gois AL, et al. Visual impairment in children with congenital Zika syndrome. J AAPOS. 2017;21(4):295-299.e2.
9. Ventura LO, Lawrence L, Ventura CV, Dutton GN, Marinho P, Ferro PF, et al. Response to correction of refractive errors and hypoaccommodation in children with congenital Zika syndrome. J AAPOS. 2017;21(6):480-4.e1.
10. Petersen LR, Jamieson DJ, Powers AM, Honein MA. Zika Virus. N Engl J Med. 2016;374(16):1552-63.
11. Shiu C, Starker R, Kwal J, Bartlett M, Crane A, Greissman S, et al. Zika Virus Testing and Outcomes during Pregnancy, Florida, USA, 2016. Emerg Infect Dis. 2018;24(1):1-8.
12. Zorrilla CD, García IG, Fragoso LG, De La Vega A, García-García I, García-Fragoso L. Zika Virus Infection in Pregnancy: Maternal, Fetal, and Neonatal Considerations. J Infect Dis. 2017;216(Supl 10):S891-S896.
13. Holtzman M, Golden WC, Sheffield JS. Zika Virus Infection in the Pregnant Woman. Clin Obstet Gynecol. 2018;61(1):177-185.
14. Sohan K, Cyrus CA. Ultrasonographic observations of the fetal brain in the first 100 pregnant women with Zika virus infection in Trinidad and Tobago. Int J Gynaecol Obstet.2017;139(3):278-283.
15. Pires P, Jungmann P, Galvão JM, Hazin A, Menezes L, Ximenes R, et al. Neuroimaging findings associated with congenital Zika virus syndrome: case series at the time of first epidemicoutbreak in Pernambuco State, Brazil. Childs Nerv Syst. 2018;34(5):957-963.
16. Parra-Saavedra M, Reefhuis J, Piraquive JP, Gilboa SM, Badell ML, Moore CA, et al. Serial Head and Brain Imaging of 17 Fetuses with Confirmed Zika Virus Infection in Colombia, South America. Obstet Gynecol. 2017;130(1):207-212.
17. Aragao MFV, van der Linden V, Regina A, Roch M, Sobral P, Durce M, et al. Clinical features and neuroimaging (CT and MRI) findings in presumed Zika virus relates congenital infection and microcephaly: Retrospective case series study. BMJ. 2016; 353:i1901.
18. Bryson Y. Zika virus congenital syndrome, the new Z in TORCHZ? Prospects for diagnosis prevention and treatment.Curr Opin Pediatr. 2017;29(1):94-96.
19. Martínez MF. Lineamientos provisionales para el abordaje clínico de gestantes expuestas al virus Zika en Colombia. Minsalud [Internet]. 2016 febr; 35. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/PP/ET/lineamientos-provionales-abordaje-clinicogestantes-expuestas-zika-colombia.pdf
20. Melorose J, Perroy R, Careas S. Lineamientos para la detección y manejo clínico integral de anomalías congénitas en fetos expuestos al virus del Zika durante la gestación de pacientes en Colombia. Minsalud [Internet]. 2016 mzo; 16. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/PP/ET/linea-deteccion-manejoclinico-nomalia-congenitas-fotos-zika.pdf
21. Vasco Aragao MF, van der Linden V, Mertens Brainer-Lima A, Ramos Coeli R, Rocha MA, Sobral da Silva P, et al. Clinical features and neuroimaging (CT and MRI) findings in presumed Zika virus related congenital infection and microcephaly: retrospective case series study. BMJ.2016;353:i1901.
22. Mlakar J, Korva M, Tul N, Popović M, PoljšakPrijatelj M, Mraz J, et al. Zika Virus Associated with Microcephaly. N Engl J Med.2016;374(10):951-8.