CLOVES syndrome. First case reported in Colombia.
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Abstract
Background: CLOVES syndrome is a rare, non-inherited genetic disorder characterized by overgrowth of any part of the body, vascular malformations, bone defects, and changes in skin color. Case report: a clinical case of CLOVES Syndrome in Barranquilla (Colombia) is presented. A nineteen-month-old female patient from Venezuela, without prior evaluations by specialists in the country of origin or residence. She comes for the first time due to feed intolerance; the overgrowth lesions were observed in this evaluation. Medical management was provided with immediate discharge due to non-affiliation with a Health Services Provider Company. Three months later, with the support of the interdisciplinary group of complex vascular anomalies (GIAV) in Buenos Aires (Argentina), the clinical diagnosis of CLOVES syndrome was made. A meeting of specialties was scheduled to start treatment. The patient died three days before the meeting due to complications associated with gastroenteritis and dehydration. Conclusions: In the case presented, it is a syndrome with overgrowth of the limbs at an early age and presents gastrointestinal complications occasionally. The diagnosis was made thanks to the collaboration of the GIAV of the Garrahan Hospital, who confirmed that the patient met all the clinical criteria. It was not possible to carry out specific therapeutic interventions due to problems of availability of the health service, with a fatal outcome three months after diagnosis.
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