Caracterización de niños y adolescentes con trastornos del espectro autista en Barranquilla, Colombia

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Ivan David De La Peña sanabria
Laury Berdejo Giovanetti
Nataly Chavarriaga Ruiz
Diana Carolina López Gulfo
Laura Marcela Rueda Manjarez
Oscar Dario Sánchez Charria
Nicolas Laza

Abstract

Introduction: Autism spectrum disorders constitute a group of neurodevelopmental disorders characterized by dysfunction of two domains, as defined by DSM V: 1) Alteration of communication and social interaction and 2) Presence of restricted behaviors, interests or activities or repetitive actions. The prevalence is on the rise worldwide, with a current frequency of 200 per 10 000 children. There is no established prevalence in Colombia, according to the Colombian Autism League. The incidence rate is on the rise, unclear if the increase is related to changes in the diagnostic criteria, the study methodology, an actual increase in the incidence of autism, or a combination of these factors. Objective: to characterize a group of patients with autism spectrum disorder and to recognize socio-environmental changes related to the population described. Methods: A descriptive observational study. Patients between 1 and 18 years of age, clinically diagnosed by neurology and child psychiatry, with autism spectrum disorder, between 2011 and 2017, in a reference center for pediatric neurological rehabilitation. Results: Data were obtained from 253 patients with autism spectrum disorders, with a mean age of symptom onset of 22.4 months (SD = 9.72) and an age at diagnosis of 43.2 months. The most frequent autism spectrum disorder was grade 1 or mild (39.5 %), the most common symptom being motor stereotypies (78.3 %), followed by interaction and social communication deficit (75.5 %). Conclusion: the importance of early recognition of clinical manifestations changes the opportunity for diagnosis and early initiation of treatment.

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How to Cite
De La Peña sanabria, I. D., Berdejo Giovanetti, L., Chavarriaga Ruiz, N., López Gulfo, D. C. . ., Rueda Manjarez, L. M. ., Sánchez Charria, O. D., & Laza , N. (2021). Caracterización de niños y adolescentes con trastornos del espectro autista en Barranquilla, Colombia. Pediatría, 54(2), 63–70. https://doi.org/10.14295/rp.v54i2.244
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Originals

References

Harrington JW, Allen K. The Clinician's Guide to Autism. Pediatrics in review. 2014;35(2) 62-78.

Lewy F. Child and Adolescent Changes to DSM-5. Asian J Psychiatr. 2014;11: 87-92.

Gyawali S, Patra BN. Trends in concept and nosology of autism spectrum disorder: A review. Asian J Psychiatr. 2019;40: 92-9.

Hodges H, Fealko C, Soares N. Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation. Transl Pediatr. 2020;9(Suppl 1): S55-S65.

Baumer N, Spence SJ. Evaluation and Management of the Child with Autism Spectrum Disorder. Continuum (Minneap Minn). 2018;24(1, Child Neurology):248-75.

Dalwai S, Ahmed S, Udani V, Mundkur N, Kamath SS, C Nair MK, et al. Consensus Statement of the Indian Academy of Pediatrics on Evaluation and Management of Autism Spectrum Disorder. Indian Pediatr. 2017;54(5):385-93.

Sharma SR, Gonda X, Tarazi FI. Autism Spectrum Disorder: Classification, diagnosis and therapy. Pharmacol Ther. 2018;190: 91-104.

Zwaigenbaum L, Brian JA, Ip A. Early detection for autism spectrum disorder in young children. Paediatr Child Health. 2019;24(7):424-43.

Cornejo Ochoa JW SM, Rodríguez Clavijo BD, Pérez Gómez ÁV, Cañón LA, Prieto LC, et al. Protocolo clínico para el diagnóstico, tratamiento y ruta de atención integral de niños y niñas con trastornos del espectro autista.: Ministerio de salud y de protección social; 2015.

Nisar S, Hashem S, Bhat AA, Syed N, Yadav S, Azeem MW, et al. Association of genes with phenotype in autism spectrum disorder. Aging (Albany NY). 2019;11(22):10742-70.

Huang J, Du C, Liu J, Tan G. Meta-Analysis on Intervention Effects of Physical Activities on Children and Adolescents with Autism. Int J Environ Res Public Health. 2020;17(6):1950.

Caron V, Bérubé A, Paquet A. Implementation Evaluation of Early Intensive Behavioral Intervention Programs for Children with Autism Spectrum Disorders: A Systematic Review of Studies in the Last Decade. Evaluation and program planning. 2017;62: 1-8.

Thabtah F, Peebles D. Early Autism Screening: A Comprehensive Review. Int J Environ Res Public Health. 2019;16(18): 3502.

Zwaigenbaum L, Penner M. Autism spectrum disorder: advances in diagnosis and evaluation. BMJ. 2018;361: k1674.

Tsai LY. The Impact of DSM-5 on autism spectrum disorder. 2015: 3-16.

Matson JL, Matheis M, Burns CO, Esposito G, Venuti P, Pisula E, et al. Examining Cross-Cultural Differences in Autism Spectrum Disorder: A Multinational Comparison from Greece, Italy, Japan, Poland, and the United States. European psychiatry: the journal of the Association of European Psychiatrists. 2017;42: 70-76.

Lobar SL. DSM-V Changes for Autism Spectrum Disorder (ASD): Implications for Diagnosis, Management, and Care Coordination for Children with ASDs. Journal of pediatric health care: official publication of National Association of Pediatric Nurse Associates & Practitioners. 2016;30(4): 359-65.

Maenner MJ, Shaw KA, Baio J, Washington A, Patrick M, DiRienzo M, et al. Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2016. MMWR Surveill Summ. 2020;69(4):1-12.

Posar A, Visconti P. Autism in 2016: The Need for Answers. J Pediatr (Rio J). 2017;93(2): 111-119.

Talero-Gutiérrez C, Rodríguez M, De La Rosa D, Morales G, Vélez-Van-Meerbeke A. Caracterización de niños y adolescentes con trastornos del espectro autista en una institución de Bogotá, Colombia. Neurología. 2020;27(2):90-6.

Chiarotti F, Venerosi A. Epidemiology of Autism Spectrum Disorders: A Review of Worldwide Prevalence Estimates Since 2014. Brain Sci. 2020;10(5):274.

Steinman G. The putative etiology and prevention of autism. Prog Mol Biol Transl Sci. 2020;173: 1-34.

Yates K, Couteur ASL. Diagnosing autism/autism spectrum disorders. undefined. Paediatrics and Child Health. 2020; 26(12):513-518.

Hadjkacem I, Ayadi H, Turki M, Yaich S, Khemekhem K, Walha, A et al. Prenatal, Perinatal and Postnatal Factors Associated with Autism Spectrum Disorder. J Pediatr (Rio J). 2016;92(6): 595-601.

Lefter R, Ciobica A, Timofte D, Stanciu C, Trifan A. A Descriptive Review on the Prevalence of Gastrointestinal Disturbances and Their Multiple Associations in Autism Spectrum Disorder. Medicina (Kaunas). 2019;56(1): 11.

Barbosa-Buck CO, Orioli IM, da Graça Dutra M, López-Camelo J, Castilla EE, Cavalcanti DP. Clinical epidemiology of skeletal dysplasias in South America. Am J Med Genet A. 2012;158A(5):1038-45.

Samsam M, Ahangari R, Naser SA. Pathophysiology of autism spectrum disorders: revisiting gastrointestinal involvement and immune imbalance. World J Gastroenterol. 2014;20(29):9942-51.

Bittker SS, Bell KR. Acetaminophen, antibiotics, ear infection, breastfeeding, vitamin D drops, and autism: an epidemiological study. Neuropsychiatr Dis Treat. 2018;14: 1399-414.

Toriello HV. Approach to the Genetic Evaluation of the Child With Autism. Pediatric clinics of North America. 2012;59(1):113-28.

Ruggieri VL, Arberas CL. [Autistic regression: clinical and aetiological aspects]. Rev Neurol. 2018;66(S01): S17-S23.

Rylaarsdam L, Guemez-Gamboa A. Genetic Causes and Modifiers of Autism Spectrum Disorder. Front Cell Neurosci. 2019;13: 385.

Becerra T, von Ehrenstein O, Heck JE, Olsen J, Arah OA, Jeste SS, et al. Autism Spectrum Disorders and Race, Ethnicity, and Nativity: A Population-Based Study. Pediatrics. 2014;134(1): e63-71.

Janeczko D, Hołowczuk M, Orzeł A, Klatka B, Semczuk A. Paternal age is affected by genetic abnormalities, perinatal complications and mental health of the offspring. Biomed Rep. 2020;12(3):83-8.

Principi N, Esposito S. Vitamin D Deficiency During Pregnancy and Autism Spectrum Disorders Development. Front Psychiatry. 2019;10: 987.

Peretti S, Mariano M, Mazzocchetti C, Mazza M, Pino MC, Verrotti Di Pianella A, et al. Diet: the keystone of autism spectrum disorder? Nutr Neurosci. 2019;22(12):825-39.

Jenabi E, Bashirian S, Khazaei S. Association between neonatal jaundice and autism spectrum disorders among children: a meta-analysis. Clin Exp Pediatr. 2020;63(1):8-13.

Magdalena H, Beata K, Paprocka J, Agnieszka KG, Szczepara-Fabian M, Buczek A, et al. Preconception Risk Factors for Autism Spectrum Disorder - A Pilot Study. Brain Sci. 2020;10(5): 293.

Li M, Francis E, Hinkle SN, Ajjarapu AS, Zhang C. Preconception and Prenatal Nutrition and Neurodevelopmental Disorders: A Systematic Review and Meta-Analysis. Nutrients. 2019;11(7):1628.

Khambadkone SG, Cordner ZA, Tamashiro KLK. Maternal stressors and the developmental origins of neuropsychiatric risk. Front Neuroendocrinol. 2020;57: 100834.

Saroukhani S, Samms-Vaughan M, Lee M, Bach MA, Bressler J, Hessabi M, et al. Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children. J Autism Dev Disord. 2019;50(9): 3341-3357.

Maher GM, O'Keeffe GW, Dalman C, Kearney PM, McCarthy FP, Kenny LC, et al. Association between preeclampsia and autism spectrum disorder: a population-based study. J Child Psychol Psychiatry. 2020;61(2):131-9.

Panjwani AA, Ji Y, Fahey JW, Palmer A, Wang G, Hong X, et al. Maternal Obesity/Diabetes, Plasma Branched-Chain Amino Acids, and Autism Spectrum Disorder Risk in Urban Low-Income Children: Evidence of Sex Difference. Autism Res. 2019;12(10):1562-73.

Sobotka SA, Francis A, Msall ME. Developmental Outcomes of Prematurity: Autism Spectrum Disorder. 2016;17 (6): e318-e324.

Wu YW, Kuzniewicz MW, Croen L, Walsh EM, McCulloch CE, Newman TB. Risk of Autism Associated With Hyperbilirubinemia and Phototherapy. 2016: 138(4): e20161813.

Zerbo O, Yoshida C, Gunderson EP, Dorward K, Croen L. Interpregnancy Interval and Risk of Autism Spectrum Disorders. Pediatrics. 2015;136(4): 651-17.

Windham GC, Pearl M, Anderson MC, Poon V, Eyles D, Jones KL, et al. Newborn vitamin D levels in relation to autism spectrum disorders and intellectual disability: A case-control study in california. Autism Res. 2019;12(6):989-98.

Bokobza C, Van Steenwinckel J, Mani S, Mezger V, Fleiss B, Gressens P. Neuroinflammation in preterm babies and autism spectrum disorders. Pediatr Res. 2019;85(2):155-65.

Conde-Agudelo A, Rosas-Bermudez A, Norton M Birth Spacing and Risk of Autism and Other Neurodevelopmental Disabilities: A Systematic Review. Pediatrics. 2016;137(5): e20153482.

Oberg AS, D’Onofrio BM, Rickert ME, Hernandez-Diaz S, Ecker JL, Almqvist C, et al. Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders. JAMA Pediatr. 2016;170(9): e160965.

Zhang T, Sidorchuk A, Sevilla-Cermeño L, Vilaplana-Pérez A, Chang Z, Larsson H, et al. Association of Cesarean Delivery With Risk of Neurodevelopmental and Psychiatric Disorders in the Offspring: A Systematic Review and Meta-analysis. JAMA Netw Open. 2019;2(8):e1910236.

Simms MD, Jin XM. Autism, Language Disorder, and Social (Pragmatic) Communication Disorder: DSM-V and Differential Diagnoses. Pediatrics in review. 2015;36(8): 356-52.

Tsang LPM, How CH, Yeleswarapu SP, Wong CM. Autism spectrum disorder: early identification and management in primary care. Singapore Med J. 2019;60(7):324-8.

Bishop SL, Thurm A, Farmer C, Lord C. Autism Spectrum Disorder, Intellectual Disability, and Delayed Walking. Pediatrics. 2016;137(3): e20152959.

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