Synchronous multicentric osteosarcoma in a 15-year-old pediatric patient: case report
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Abstract
Background: Cancer in the pediatric population is between 2 to 3% of all malignant tumors. The most frequent tumors in children are leukemias (30%), brain tumors (20%), and lymphomas (15%). Bone tumors represent 6% of neoplasms in children; osteosarcoma constitutes 55% of cases, with a peak incidence at 15 years. This neoplasia has an aggressive behavior with metastasis of approximately 15% at the time of diagnosis, the lungs being the most frequent site followed by bone, lymph nodes, liver, and brain. When the diagnosis shows more than one bone lesion without visceral metastasis, the term multicentric and synchronous is added; this entity is of rare appearance, with a report of fewer than 100 cases in the literature. Case report: In the following case, we present a 15-year-old patient with disabling pain in the left lower limb and images suggestive of synchronous multicentric bone neoplasm and biopsy that concluded chondrogenic variant osteosarcoma. Conclusion: The patient received palliative cancer treatment and later presented pulmonary metastasis. This variant of osteosarcoma is extremely aggressive with a very poor prognosis.
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